Download PDF Methylisocitrate Lyase
Methylisocitrate Lyase Wade Anastasia Jere
Published Date: 25 Dec 2011
Publisher: Equ Press
Language: English
Format: Paperback::80 pages
ISBN10: 6200038465
ISBN13: 9786200038463
File size: 23 Mb
Filename: methylisocitrate-lyase.pdf
Dimension: 152x 229x 5mm::127g
Download PDF Methylisocitrate Lyase. Mtb's ICLs are catalytically bifunctional isocitrate and methylisocitrate lyases required for growth on even and odd chain fatty acids. Here, we Crystal structure of Salmonella typhimurium 2-methylisocitrate lyase (PrpB) and its complex with pyruvate and $Mg^2+$. Simanshu The Saccharomyces cerevisiae ICL2 Gene Encodes a Mitochondrial 2-Methylisocitrate Lyase Involved in Propionyl-Coenzyme A Metabolism TTER,2 FLORIAN 1XG3: Crystal structure of the C123S 2-methylisocitrate lyase mutant from Escherichia coli in complex with the reaction product, Mg(II)-pyruvate and succinate. Isocitrate lyase is important for lipid utilisation Mycobacterium substantially increasing isocitrate lyase and methylisocitrate lyase activities. Crystal Structures of 2-Methylisocitrate Lyase in Complex with Product and with Isocitrate Inhibitor Provide Insight into Lyase Substrate pyruvate and glyoxylate, would be supplied isocitrate lyase, the first unique enzyme as it serves also as the 2-methylisocitrate lyase which mitochondrial Plastidial pyruvate kinase 2 Citrate (Pro-3S)-lyase beta subunit SC:2 Probable isocitrate lyase protein Probable methylisocitrate lyase 2 SC:3 B receptor precursor, 5611, 7701, 1. CDS, prpB, ZP_03345904.1, Salmoneentericaenterica_010100008983, 2-methylisocitrate lyase, 10908, 11795, 1. YP_884315 hypothetical protein. 5.97. MAV_0345. YP_879632 methylisocitrate lyase. 5.56. MAV_2086. YP_881301 ornithine -oxo-acid transaminase. 5.07. The enzyme 2-methylisocitrate lyase (PrpB) from Escherichia coli catalysing the last step of this cycle, the cleavage of 2-methylisocitrate to pyruvate and 2-methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate; Belongs to Burkholderia sacchari IPT101(T) induced the formation of 2-methylcitrate synthase and 2-methylisocitrate lyase when it was cultivated in the presence of Distinction between isocitrate lyase and methylisocitrate lyase in Candida lipolytica, Agricultural Biological Chemistry, 40, 1863 1869. TABUCHI, T and SATOH, cgm:cgp_0760(307), 307, 100.0, 1974, (424), 3, <>, K03417 prpB, prpB2; methylisocitrate lyase, involved in propionate catabolism; K03417 methylisocitrate We then tested the methylisocitrate lyase activity of Mtb ICL2; no methylisocitrate lyase activity was detected with Mtb ICL2 alone (Fig. also described on: isocitrate lyase from Escherichia coli, Mycobacterium tuberculosis, Pseudomonas indigofera and 2-methylisocitrate lyase, Methylcitrate cycle defines the bactericidal essentiality of isocitrate lyase for Crystal structures of 2-methylisocitrate lyase in complex with product and with Methylisocitrate lyase. Hence, this enzyme has one substrate, (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate (also known as 2-methylisocitrate), and two products, pyruvate and succinate. This enzyme belongs to the family of lyases, specifically the oxo-acid-lyases, which cleave carbon-carbon bonds.
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